Clinical Pharmacology
Cockcroft-Gault Creatinine Clearance (CrCl)
CrCl (mL/min) = [(140 - Age) × Weight (kg)] / [72 × Serum Cr (mg/dL)] × (0.85 if female)
Target Output: Creatinine Clearance (CrCl) (CrCl)[SOLVED]
77.777778
mL/minEstimated creatinine clearance
yr
Patient age
Patient weight
Serum creatinine concentration
Gender correction factor
💡 What This Is Useful For: Dosing renally cleared drugs, adjusting chemotherapy protocols, and assessing renal function.
📐 Real-World Worked Example: A 60-year-old male weighing 70 kg with serum Cr of 1.0 mg/dL: CrCl = (140 - 60) * 70 / (72 * 1.0) * 1 = 77.78 mL/min.
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Scientifically reviewed by:D Yap, MBiochem (Oxon), DIC, PhD (Lond)
Clinical Medicine Research Scientist·LinkedIn Profile ↗·ORCID: 0000-0002-5370-4592 ↗
⚠️ Research Reference Notice: For reference and research education only. Reviewer is a clinical medicine research scientist and not a practicing physician or veterinarian, and does not provide clinical certification or medical advice. Experimental drug doses and clinical measurements must be verified against institutional protocols, primary manufacturer labeling, and physician orders.